ABSTRACT
OBJECTIVE@#To study the value of the pepsin in the sputum for diagnosing and evaluating the effectiveness of treatment of laryngopharyngeal reflux.@*METHOD@#Thirty-six patients with the symptoms of dry pharynx, globus pharyngeus, excessive throat clearing, chronic cough and so on were divided into laryngopharyngeal reflux group and chronic laryngitis group by the results of therapeutic trial taking proton pump inhibitors for 3 months. The estimation of the reflux symptom index (RSI), the reflux finding score (RFS) and the detection of pepsin in the sputum were done before and after the treatment. The difference between two groups and the value of the pepsin were analyzed.@*RESULT@#There were significant decreasing in RSI, RFS and pepsin level (P < 0.01) after the treatment in all patients. There were statistical differences between the laryngopharyngeal reflux group and the chronic laryngitis group in the changes of RSI and pepsin level (P < 0.01).@*CONCLUSION@#Pepsin level in the sputum might be used as a objective, effective method for diagnosing and evaluating the effectiveness in laryngopharyngeal reflux.
Subject(s)
Adult , Female , Humans , Male , Middle Aged , Young Adult , Laryngopharyngeal Reflux , Diagnosis , Therapeutics , Pepsin A , Sputum , Chemistry , Treatment OutcomeABSTRACT
Objective:To observe the clinical effect of Xingnao Yizhi Pills on vascular dementia.Methods:Eighty-five patients suffering from vascular dementia were randomly divided into two groups,the treatment group(n=55)and the control group(n=30).The treatment group took a dose of 6g of Xingnao Yizhi Pills orally,twice a day.The control group was given 20ml Cerebrolysin with 250ml of 0.9%saline intravenous drip.They were also given 20ml Mailuoning and 0.5g of Cytidine Diphosphate Choline CDPC with 0.9%saline intravenous drip once a day.The treatment of the two groups lasted two months. Results:The total efficiency of the treatment group(92.7%)was obviously higher than that of the control group(73.3%)(P